Revealing the 80 Game-Changing Deep Tech Startup Finalists

From over 4,600 applications, 80 deep tech projects remain in the race to win.

As we enter the 10th edition of the Hello Tomorrow Global Summit, our mission remains unchanged: to spotlight the boldest entrepreneurs pushing the boundaries of science and technology. After a rigorous selection process, only 80 Deep Tech startups remain in the running for the 2025 Hello Tomorrow Global Challenge, the world’s leading competition for breakthrough innovations.

Selected from over 4,600 applications, these pioneering startups are tackling some of the most pressing challenges across industries, from AI-powered medical diagnostics and sustainable construction to next-generation energy solutions and aerospace innovation. In addition to global recognition, they will compete for the €100,000 grand prize, with winners announced at the Hello Tomorrow Global Summit on March 13-14, 2025, in Paris.

Hello Tomorrow was founded with a profound respect for entrepreneurs, those who take action to solve pressing challenges rather than just pointing them out. Whether they’re building ambitious startups or driving change within large organizations, these innovators are influencing the future” said Arnaud de la Tour, CEO at Hello Tomorrow.

“Seeing this year’s 80 exceptional finalists is a powerful reminder of why we do what we do. It makes us incredibly proud to support them. Once again, this year has proven that solutions exist, whether it’s climate resilience technology enabled by machine learning, wastewater treatment for increasing drinking water access, or other game-changing innovations. Our goal is to bring these technologies to market, where they can create real impact.

I look forward to meeting these visionary teams at the Hello Tomorrow Summit, watching their journeys accelerate through invaluable connections with investors and potential clients.In today’s challenging times, this kind of optimism is more important than ever.”

Discover the Most Radical Innovations Across Key Industries

Beyond technological excellence, these finalists stand out for their vision, leadership, and economic potential. Now, let’s meet the innovators shaping the future.

80 revolutionary projects classified into 10 categories:

Advanced Computing & Electronics supported by Murata 

 

Belfort (Belgium) 

Belfort develops advanced cryptographic techniques that enable data processing while keeping it encrypted. This technology facilitates new and valuable applications for highly sensitive data, particularly in privacy-preserving AI, medical research (personalised healthcare), and financial services (fraud detection).

 

Equal1 (Ireland) 

Equal1 is transforming quantum computing with its QSoC processors, integrating the entire quantum system onto a single chip using established semiconductor processes.

 

Gallox Semiconductors Inc. (United States) 

Gallox is developing Ga₂O₃-based diodes and transistors for power inverters, enabling more efficient power conversion for data centres and EV chargers.

 

nanoLambda (South Korea) 

nanoLambda is revolutionising 300-year-old spectrometer technology with a novel digital nano-technology approach, creating the world’s smallest spectrometer—less than 0.1% of the size and cost of conventional solutions—enabling non-invasive material analysis in everyday life.

 

Qruise GmbH (Germany) 

Qruise develops solutions for quantum technology advancement, focusing on quantum computation. Its methodology is also applied to quantum sensing, MRI, silicon photonics, and other fields.

 

SixLine Semiconductor, Inc. (United States) 

SixLine Semiconductor is enabling next-generation electronics by solving a 30-year challenge in carbon nanotube alignment, delivering faster, more energy-efficient devices at a lower cost.

 

Ubitium (Germany) 

​​Ubitium is developing a universal RISC-V microprocessor, addressing computing complexity and cost challenges to create a future where every device is autonomous.

Aerospace supported by Safran

 

Alpha Impulsion (France) 

Alpha Impulsion pioneers hybrid autophage rocket technology, where the launcher’s structure is entirely consumed as fuel, doubling performance while minimising space debris.

 

ColdXray (Finland) 

ColdXray develops efficient, durable graphene-based cold-cathode electron and X-ray sources, transforming space exploration, medical imaging, and industrial testing.

 

Connected (Portugal) 

Connected utilises space technology to revolutionise connectivity for individuals and industries, delivering universal, standardised, and cost-effective narrowband IoT connectivity from space.

 

Dovetail Electric Aviation (Australia) 

Dovetail Electric Aviation is leading regional aviation into a sustainable future by enabling operators to fly commercially viable, zero-emission, electric-powered aircraft.

 

Flux Aviation (United Kingdom) 

Flux Aviation is developing ultra-high-performance electric motors and batteries to power next-generation electric aircraft.

 

FVMat (Israel) 

FVMat bridges the gap in engineering potential by developing materials with transformative properties, integrating cutting-edge computational tools with advanced machine learning.

 

Phigi (France) 

Phigi develops microrobots powered by sunlight that can self-assemble into various forms, such as shields, power or data lines, solar panels, antennas, and more.

 

Digital Health & Medical Devices

 

AreteMedical (United Kingdom)  

AreteMedical has developed a low-cost, portable, web-connected, and rapid-use platform for testing lung inflammation, obstruction, and narrowing, enabling earlier intervention for chronic lung diseases like asthma.

 

cureVision GmbH (Germany) 

cureVision is revolutionising the analysis, diagnosis, and treatment of chronic wounds with cutting-edge sensors and computer vision, enabling 90% faster monitoring.

 

Impli (United Kingdom)  

Impli is transforming healthcare by introducing high-precision remote monitoring through an innovative real-time hormone monitoring implant for IVF treatments.

 

Lura Health (United States) 

Lura Health enables non-invasive health monitoring with first-in-class salivary diagnostic wearable sensors, which have the potential to improve clinical outcomes in chronic disease management.

 

PerMe (Israel) 

PerMe is at the forefront of health technology, pioneering the world’s first digital DNA test. By converting biological samples into digital data, it is revolutionising DNA diagnostics.

 

Physiologas Technologies Inc. (Japan) 

Physiologas Technologies has developed a groundbreaking waterless, home-use haemodialysis system that recycles dialysate within the device, eliminating the need for plumbing.

 

Vivalyx | Organ Vitality Tech (Germany) 

Vivalyx introduces a solution for making perfusion at body temperature scalable, using a blood-replacing organ revitalisation platform to enhance the vitality and availability of donor organs.

Energy supported by Honda Xcelerator Ventures and GTT

 

COnovate, Inc. (United States) 

COnovate is a seed-stage company developing a unique nanomaterial for lithium-ion and sodium-ion batteries, offering a sustainable and localised supply chain alternative to environmentally damaging mined materials.

 

ElectraLith (Australia)  

ElectraLith is unlocking a greener future with the cleanest, most versatile, and most cost-efficient method of extracting and refining lithium, a key element in sustainable energy solutions.

 

Found Energy (United States) 

Found Energy is providing an affordable, safe, and ethical alternative to fossil fuels by using abundant and energy-dense aluminium metal as a carbon-free fuel capable of generating high-temperature heat or hydrogen for industrial applications.

 

ICODOS (Germany)

ICODOS is revolutionising large-scale e-methanol production with a cost-effective, energy-efficient, and sustainable approach, aiming to decarbonise the shipping and chemical industries.

 

ReCatalyst (Slovenia) 

ReCatalyst is building a groundbreaking nanotechnology platform for producing advanced (electro)catalysts for fuel cells and water electrolysis, optimising platinum group metal use for decarbonising the energy and transport sectors.

 

Rockburst Technologies Inc. (Canada) 

Rockburst Technologies is developing an innovative particle reduction method that uses CO₂ to break mineral ore and other materials from within, reducing costs, energy consumption, and greenhouse gas emissions by 50%.

 

Wildfire Energy (Australia)  

Wildfire Energy produces renewable electricity, hydrogen, and sustainable fuels from residual waste, such as domestic garbage, that would otherwise end up in landfills or incinerators.

Environment & Biodiversity supported by L’Oréal 

 

Arbon (United States) 

Arbon has developed a technology that adsorbs and desorbs atmospheric CO₂ by modulating humidity around the substrate. Using water as a regenerative technique eliminates the need for energy-intensive and heat-based processes that hinder the economic viability of most direct air capture (DAC) systems.

 

Blusink Ltd.(United Kingdom) 

Blusink is pioneering regenerative and permanent carbon capture through accelerated seafloor engineering.

 

DARWIN Bioprospecting Excellence (Spain) 

DARWIN Bioprospecting Excellence is an advanced bioprospecting company that harnesses microbial diversity to develop industry-relevant solutions.

 

Dryad Networks GmbH (Germany) 

Dryad provides solar-powered, AI-enabled gas sensors that detect wildfires as early as the smouldering phase.

 

RainbirdGEO (South Korea)  

RainbirdGEO is an innovative climate technology company developing the world’s first mobile early warning system to rapidly deliver climate risk information.

 

SXD (United States) 

SXD uses patented AI to eliminate material waste, creating zero-waste products with approximately 80% lower CO₂ emissions at reduced costs.

 

UP Catalyst (Estonia) 

UP Catalyst transforms industrial CO₂ emissions into high-value graphite and carbon nanomaterials for energy storage applications.

 

Food & Agriculture supported by DSM-Firmenish  and Avril

 

Biocentis (United Kingdom) 

Biocentis is redefining insect control with a powerful and scalable genetic platform that combines environmental sustainability with unprecedented cost-effectiveness.

 

Codomax (United States)  

​​Codomax’s Epi-MAX platform enables the production of previously impossible-to-manufacture proteins by re-engineering cellular stress responses. This breakthrough technology makes complex biologics and nature-identical proteins accessible and affordable, revolutionising both therapeutic development and sustainable food production.

 

Hypesound (Italy) 

Hypesound has developed So’ Sweep, a technology designed to transform the fermentation market by using low-frequency sound waves to increase microorganism reproduction by up to 300% while enhancing purity levels.

 

M4Life (Argentina) 

M4Life harnesses bio-trained microbes to convert degraded lands into thriving agricultural ecosystems, enabling crops to flourish in challenging environments. Their pioneering technology not only boosts yields and nutrition but also combats deforestation by making existing farmland more productive.

 

Nosh.bio (Germany) 

Nosh.bio leverages natural biomass fermentation to offer clean-label, tasty, nutritious, and sustainable solutions for a diverse range of products, including meat and seafood analogues, sauces, confectionery, dairy, bakery, health and wellness items, and beverages.

 

Nūmi (France) 

Nūmi produces human breast milk using cell culture to provide infants with ideal nutrition when breastfeeding is not an option.

 

SioValley Technologies Limited (SVT) (Uganda) 

SVT enhances Africa’s post-harvest handling with an innovative edible coating solution that extends the shelf life of produce at room temperature from 5 to 180 days.

 

Industrial Biotech & New Materials supported by Syensqo and Biotope Ventures

 

Bioeutectics (United States) 

Bioeutectics is revolutionising the solvents industry by replacing petrochemical solvents with high-performance, nature-derived deep eutectic solvents for industrial processes.

 

Boreal Bioproducts (Finland) 

Boreal Bioproducts upcycles residual wood streams from industrial sources using a low-chemical, water-based biorefinery process to produce biochemicals such as polysaccharides and lignin polyphenols.

 

BUYO Bioplastics Company Limited (Vietnam) 

BUYO transforms abundant bio-waste into premium biodegradable materials that match plastic’s performance while leaving no environmental trace. Their proprietary technology creates tailored solutions for global brands across industries, turning waste management into a circular opportunity.

 

Level Nine (Germany) 

Level Nine combines bio-nanotechnology and quantum chemistry to create enzyme-inspired catalysts that thrive in industrial conditions. Their breakthrough catalysts bridge the gap between crude traditional methods and fragile enzymes, unlocking a pathway to profitable, fossil-free chemical manufacturing.

 

Qorium B.V. (Netherland) 

Qorium is a synthetic biology startup developing a cellular agriculture and tissue engineering platform to produce real leather. The result is high-quality, durable leather with a drastically reduced environmental impact compared to cow-derived sources.

 

Retein (Sweden) 

Retein is developing separation membranes that efficiently recover waterborne resources with molecular precision for circular use.

 

spotLESS Materials Inc. (United States) 

spotLESS Materials pioneers PFAS-free, nature-inspired coatings that create ultra-slippery surfaces repelling liquids, solids, and biological materials. Their patented LESS technology transforms everyday surfaces into self-cleaning, low-friction interfaces, revolutionising both consumer products and industrial applications.

Industry & Machines

 

AddOptics ( Netherlands) 

AddOptics revolutionises AR smart glasses with customisable prescription lenses that seamlessly integrate advanced display technologies. Their manufacturing breakthrough enables sleek, everyday-wearable AR devices that deliver immersive experiences without compromising style or optical performance.

 

Carbon Re ( United Kingdom) 

Carbon Re develops AI-powered software to decarbonise cement and other foundational materials such as steel and glass, which are responsible for more than 20% of global emissions.

 

EcoNautik (France) 

EcoNautik empowers marine service centres and distributors to decarbonise boats by offering boat owners a fast, reliable, and affordable conversion of existing engines to hydrogen or biogas combustion, reducing operating costs and greenhouse gas emissions.

 

Elythor SA ( Switzerland)

Elythor develops innovative drone technologies for frequent, on-demand inspections of energy assets in extreme weather conditions. Their drones perform hybrid missions in complex terrains, remote locations, and marine environments.

 

Fluid Wire Robotics (Italy) 

Fluid Wire Robotics builds next-generation robotic arms for extreme environments—nuclear, space, underwater, and beyond. Our fluidic transmission technology delivers unmatched precision, power, and versatility, enabling safer, more efficient unmanned operations across critical industries.

 

RESONIKS (Netherlands) 

RESONIKS detects anomalies by resonating objects and analysing their acoustic response using AI. This technology allows manufacturers to identify structural defects such as cracks, pores, and cavities in metal parts, serving the automotive, aerospace, maritime, and machine-building sectors.

 

Sunchem (United States) 

Sunchem is developing Nano Leach and Nano Filter technologies for the precision separation of critical metals. These technologies, designed for high-value markets such as electronic waste recycling, mining, and energy, replace inefficient separation techniques that are non-selective, prone to fouling, and environmentally unfriendly.

 

 Medical Biotech & Pharmaceuticals

 

Aptah Bio (United States) 

Aptah Bio has developed RNA Widespread Correction (RNA WiCo™), a pioneering RNA rejuvenation platform that enables the rational design of synthetic molecules to edit, modulate, and control the expression of multiple RNAs.

 

Captain T Cell (Germany) 

Captain T Cell develops first-in-class, efficacy-enhanced T cell therapies for solid tumour patients who currently have no treatment options. Their novel, proprietary allogeneic platform enables off-the-shelf treatment solutions.

 

Dillico (France) 

Dillico is transforming mRNA pharmaceutical development by radically simplifying the mRNA manufacturing process.

 

HEPHAISTOS Pharma (France) 

HEPHAISTOS Pharma enhances immunotherapies by stimulating the patient’s immune response, turning cold tumours into hot targets for the immune system.

 

Portal Biotechnologies (United States) 

Portal Biotechnologies is enabling next-generation cell engineering with a proprietary mechanical delivery system that can deliver diverse cargo types to a broad range of cell types using a compact silicon chip.

 

Prometheus Life Technologies (Switzerland) 

Prometheus Life Technologies uses cutting-edge technology to grow organoids in space, addressing the demand for organ and tissue material for transplantation, drug development, disease modelling, and preclinical drug testing.

 

TheraSonic (France) 

TheraSonic is revolutionising the treatment of neurological diseases with brain-targeted drug delivery. Using non-invasive focused ultrasound on intravenously injected gas microbubbles, they temporarily and safely disrupt the blood-brain barrier to improve drug delivery.

 

Sustainable Construction & Infrastructure

 

AeroShield Materials (United States) 

AeroShield creates ultra-clear, super-insulating silica aerogels that boost window efficiency by 65%, outperforming triple-pane glass at a lower cost.

 

Automated Architecture Limited (United Kingdom) 

AUAR powers a network of robotic micro-factories that automate timber home construction, making sustainable housing more affordable.

 

Extracthive (France) 

Extracthive is dedicated to the circular economy, developing innovative technology to recycle carbon fibre-reinforced polymers.

 

NanoChronia (Spain) 

NanoChronia offers advanced IoT semiconductor nanosensor systems that detect and quantify leaks of hydrogen, methane, ammonia, and hydrogen sulphide in real time.

 

ParaStruct (Austria) 

Parastruct transforms construction sustainability with a proprietary recycling process that reactivates mineral binders, cutting CO2 emissions by 70%. Their technology licenses empower B2B partners to reduce environmental impact at scale.

 

Ultra High Materials, Inc. (United States) Ultra High Materials (UHM) pioneers advanced cementitious materials that replace Portland cement, cutting CO2 emissions by 80% while enhancing strength and durability. They offer scalable, cost-effective solutions that transform concrete production for a sustainable future.

 

VacuumWood.tech (Finland) VacuumWood.tech pioneers vacuum-dryable wood construction modules with IoT monitoring, ensuring moisture resistance in extreme conditions. This breakthrough technology extends wood durability, revolutionizing sustainable building solutions.

 

Emerging Deep Tech Pioneers

Emerging deep tech pioneers are early-stage startups developing groundbreaking innovations rooted in scientific discoveries and advanced engineering. The startups recognized in this category are not only demonstrating technological excellence but also proving their potential for real-world impact.

 

Advanced Computing & Electronics

Alpha3D (Estonia) Automatically transforms your 2D images and text prompts into 3D digital assets in seconds. 

 

Aerospace

ALATYR (France) ALATYR democratizes space-based research and manufacturing through autonomous platforms, making microgravity experiments accessible beyond traditional space stations. Their robotized solutions unlock new possibilities in pharma, biotech, and materials science.

 

Digital Health

Papcup (United Kingdom) Papcup is a handheld, non-invasive device that uses an electrochemical biosensor to detect cancer-causing HPV in menstrual blood. Designed to offer a dignified alternative to traditional cervical screenings, Papcup provides instant results directly to the user. 

 

Energy

Pioniq Technologies (France) Pioneering sustainable energy storage without lithium or rare metals, Pioniq Technologies harnesses abundant materials to create next-generation batteries that are safer, cleaner, and more accessible. 

 

Environment & Biodiversity

BeeOdiversity (Belgium) Using wild bees as nature’s environmental sensors, BeeOdiversity combines AI and biological data to monitor and restore ecosystem health at scale. Their BeeOmetrics platform transforms bee behavior into actionable insights, helping land managers and policymakers make data-driven decisions for biodiversity protection.

 

Food & Agriculture

AI Bobby.com (France) AI Bobby harnesses generative AI to fast-track the development of alternative proteins that match and exceed traditional animal proteins in taste and functionality. Their technology transforms food innovation by reducing development time and increasing success rates, accelerating the path to sustainable protein solutions.

 

Industrial Biotech & New Materials

SUSPOL Polimeros Sostenibles (Spain) SUSPOL is transforming the bioplastics industry with our continuous-flow PLA production process, and our new flexible and recyclable bioplastic FLEXsus®.

 

Industry & Machines

GraphiCore (Italy) GraphiCore revolutionizes nuclear decommissioning with patented tools that safely extract and handle graphite from retired reactors. Their technology transforms a critical industry bottleneck into a streamlined, cost-effective process, accelerating the path to sustainable nuclear facility closure.

 

Medical Biotech & Pharmaceuticals

ImnoTech GmbH (Germany) ImuVeo’s breakthrough imaging technology tracks T-cell responses in cancer patients, cutting immunotherapy assessment time from months to weeks. Their novel diagnostic tool enables faster treatment decisions and better patient outcomes by quickly identifying who is responding to therapy.

 

Sustainable Construction & Infrastructure

Uberbinder Limited (United Kingdom) revolutionizes road construction with a bio-polymerized sulfur binder that eliminates the need for fossil-based bitumen. Their drop-in solution not only decarbonizes global infrastructure but delivers more durable, climate-resilient roads at scale.

 

This year’s deep tech startup finalists are pioneering solutions in bioprinted organs, AI-driven drug discovery, quantum computing, and advanced carbon capture. Emerging trends include nanoparticle-based drug delivery, at-home cancer diagnostics, sustainable mineral extraction, next-gen superconductors and processors, bio-based construction materials, and bioinformatics for synthetic biology.

 

Want to hear them pitch? Get your pass and join over 3,000 industry leaders, investors, founders and ecosystem builders at this year’s Hello Tomorrow Global Summit, on March 13-14, 2025, in Paris.

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